Structure via PubChem · Public domain (PubChem)
ropinirol
Sign in to saveAlso known as Requip®, SK&F-101468-A, SK&F-101468A, Ropinirole, Ropinirolum
Ropinirole, sold under the brand name Requip among others, is a medication used to treat Parkinson's disease (PD) and restless legs syndrome (RLS). It is taken by mouth.
Chemical data
- Formula
- C16H24N2O
- Molecular weight
- 260.37 g/mol
- IUPAC name
- 4-[2-(dipropylamino)ethyl]-1,3-dihydroindol-2-one
- SMILES
- CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1
- InChIKey
- UHSKFQJFRQCDBE-UHFFFAOYSA-N
- XLogP
- 2.7
- Polar surface area
- 32.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
1,116 papers- Ropinirole.2006
- Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery.Cell stem cell · 2023
- [Ropinirol: a new dopamine agonist in the treatment of Parkinson's disease].Neurologia (Barcelona, Spain) · 1997
- [Systemic review and meta-analysis of tolerability and safety between different titration regimes of ropinirol dose in the treatment of Parkinson's disease].Neurologia (Barcelona, Spain) · 2007
- Dopamine agonists.The Medical clinics of North America · 1999
via PubMed
Wikidata facts
- Mass
- 260.188863
Show 6 more facts
- chemical formula
- C₁₆H₂₄N₂O
- canonical SMILES
- CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1
- World Health Organisation international non-proprietary name
- ropinirole
- defined daily dose
- 6
- stylized name
- rOPINIRole
- Commons category
- Ropinirole
via Wikidata · CC0
~6 min read
Article
11 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Lawsuit
- See also
- References
Ropinirole, sold under the brand name Requip among others, is a medication used to treat Parkinson's disease (PD) and restless legs syndrome (RLS). It is taken by mouth.
Common side effects include sleepiness, vomiting, and dizziness. Serious side effects may include pathological gambling, hypersexuality, low blood pressure with standing and hallucinations. Use in pregnancy and breastfeeding is of unclear safety. It is a dopamine agonist and works by triggering dopamine D2 receptors.