Structure via PubChem · Public domain (PubChem)
rosoxacin
Sign in to saveAlso known as Roxadyl, ROS, Acrosoxacin, WIN-35213, Rosoxacine, Rosoxacino, Rosoxacinum
Rosoxacin (also known as acrosoxacin, tradename Eradacil) is a quinolone antibiotic indicated for the treatment of urinary tract infections and certain sexually transmitted diseases. Rosoxacin is not available in the United States.
In the Vinony graph
Vinony's link graph records 118 inbound references to rosoxacin, and connects out to sulfamethazine, quinolone antibiotic and fidaxomicin.
It is catalogued under topics including 4-Pyridyl compounds, Carboxylic acids and Drugboxes which contain changes to verified fields.
Vinony links it to 12 Wikipedia language editions.
Chemical data
- Formula
- C17H14N2O3
- Molecular weight
- 294.3 g/mol
- IUPAC name
- 1-ethyl-4-oxo-7-pyridin-4-ylquinoline-3-carboxylic acid
- SMILES
- CCN1C=C(C(=O)C2=C1C=C(C=C2)C3=CC=NC=C3)C(=O)O
- InChIKey
- XBPZXDSZHPDXQU-UHFFFAOYSA-N
- XLogP
- 0.6
- Polar surface area
- 70.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- bacterial disease
via ChEMBL · EBI
Research
112 papers- Rosoxacin in the therapy of uncomplicated gonorrhea.Antimicrobial agents and chemotherapy · 1984
- Rosoxacin (Win 35,213) in the treatment of uncomplicated acute gonococcal infection.Clinical therapeutics · 1982
- Inhibition of IRAK1 Is an Effective Therapy for Autoimmune Hypophysitis in Mice.International journal of molecular sciences · 2022
- Rosoxacin and cinoxacin distribution in prostate, vagina, and female urethra. An experimental study in dogs.Investigative urology · 1979
- In-vitro antigonococcal activity of rosoxacin (WIN 35213).The British journal of venereal diseases · 1981
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 294.1
- Has use
- medication
Show 6 more facts
- MCN code
- 2933.49.12
- chemical formula
- C₁₇H₁₄N₂O₃
- canonical SMILES
- CCN1C=C(C(=O)C2=C1C=C(C=C2)C3=CC=NC=C3)C(=O)O
- World Health Organisation international non-proprietary name
- rosoxacin
- defined daily dose
- 0.3
- Commons category
- Rosoxacin
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Rosoxacin (also known as acrosoxacin, tradename Eradacil) is a quinolone antibiotic indicated for the treatment of urinary tract infections and certain sexually transmitted diseases. Rosoxacin is not available in the United States.
It was developed in 1978 by George Lesher and his colleagues at Winthrop-Stearns (now part of sanofi-aventis), as an extension of the work that originally led to nalidixic acid.
Excerpted from Wikipedia’s “rosoxacin” article, available under the CC BY-SA 4.0 licence.