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securinine

Structure via PubChem · Public domain (PubChem)

EntityQ4413415· pop 5· linked from 200 articles

securinine

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Also known as (-)-securinine

Securinine is an alkaloid found in Securinega suffruticosa and Phyllanthus niruri.

Chemical data

Formula
C13H15NO2
Molecular weight
217.26 g/mol
IUPAC name
(1S,2R,8S)-14-oxa-7-azatetracyclo[6.6.1.01,11.02,7]pentadeca-9,11-dien-13-one
SMILES
C1CCN2[C@H](C1)[C@]34C[C@H]2C=CC3=CC(=O)O4
InChIKey
SWZMSZQQJRKFBP-WZRBSPASSA-N
XLogP
1.1
Polar surface area
29.5 Ų
H-bond donors
0
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Has part
carbon
Mass
217.110279
Show 3 more facts
canonical SMILES
C1CCN2C(C1)C34CC2C=CC3=CC(=O)O4
chemical formula
C₁₃H₁₅NO₂
isomeric SMILES
C1CCN2[C@H](C1)[C@]34C[C@H]2C=CC3=CC(=O)O4
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections
Contents
  • Pharmacology
  • See also
  • References

Securinine is an alkaloid found in Securinega suffruticosa and Phyllanthus niruri.

== Pharmacology == Securinine has pro-convulsant effects and it has a strong spastic effect, similar to the actions of strychnine.

Excerpted from Wikipedia’s “securinine” article, available under the CC BY-SA 4.0 licence.

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