Also known as SEMAE, SemE, semaphorin 3C
Semaphorin-3C is a protein that in humans is encoded by the SEMA3C gene.
This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease. [provided by RefSeq, May 2017].
via MyGene.info
Semaphorin-3C is a protein that in humans is encoded by the SEMA3C gene.
== References ==
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).