انحلال الشيخوخة
Sign in to saveAlso known as senolytic, Senotherapeutics
A senolytic (from the words senescence and -lytic, "decomposition or breakdown") is among a class of small molecules under basic research to determine if they can selectively induce death of senescent cells and improve health in humans. A goal of this research is to discover or develop agents to delay, prevent, alleviate, or reverse age-related diseases. Removal of senescent cells with senolytics has been proposed as a method of enhancing immunity during aging.
In the Vinony graph
Within Vinony's link graph, انحلال الشيخوخة is referenced by 45 other articles, and connects out to heat shock protein Hsp90 family, cancer and pH.
It is catalogued under topics including Anti-aging substances, Senescence and Senescence in non-human organisms.
Its subject is documented across 10 Wikipedia language editions.
Research
2,641 papers- Cellular senescence and senolytics: the path to the clinic.Nature medicine · 2022
- Targeting cellular senescence with senotherapeutics: senolytics and senomorphics.The FEBS journal · 2023
- The Role of Senolytics in Osteoporosis.Biomolecules · 2025
- Targeting Senescence: A Review of Senolytics and Senomorphics in Anti-Aging Interventions.Biomolecules · 2025
- The potential of Senolytics in transplantation.Mechanisms of ageing and development · 2021
via PubMed
Article · العربية
يعتبر محلل الشيخوخة (بالإنجليزية: Senolytic)-المكون من كلمتين «هرم» و «محلل»- من فئة الجزيئات الصغيرة التي تخضع للبحث الأساسي لتحديد ما إذا كان يمكنها تحفيز موت الخلايا المسنة بشكل انتقائي،ويعد الهدف الذي يسعى إليه أولئك الذين يعملون على تطوير عوامل التحلل هو تأخير أو منع أو تخفيف أو عكس الأمراض المرتبطة بالعمر، فمضاد كلمة "senolytic" هو "senostatic" وهو ما يعني قمع الشيخوخة.
Abstract from DBpedia / Wikipedia · CC BY-SA