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GeneQ18029182· pop 7· linked from 820 articles

Also known as AFX, AFX1, MLLT7, forkhead box O4

Forkhead box protein O4 is a protein that in humans is encoded by the FOXO4 gene.

Gene data

FOXO4
Name
forkhead box O4
Type
protein-coding
Chromosome
X
Position
71,095,851–71,103,535 (+)
Aliases
AFX, AFX1, MLLT7
RefSeq RNA
NM_001170931.2, NM_005938.4
RefSeq protein
NP_001164402.1, NP_005929.2

This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010].

via MyGene.info

Gene · Ensembl

forkhead box O4

Symbol
FOXO4
Biotype
Protein coding
Organism
Homo sapiens
Location
Chr X:71,095,839-71,103,535
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein MLLT7 PDB 1e17.png
Show 5 more facts
HomoloGene ID
4342
genomic end
71103532
genomic start
71095851
cytogenetic location
Xq13.1
Sources (4)

via Wikidata · CC0

~4 min read

Article

9 sections
Contents
  • Structure and function
  • Clinical significance
  • Associations with longevity
  • Cancer
  • Interactions
  • See also
  • References
  • Further reading
  • External links

Forkhead box protein O4 is a protein that in humans is encoded by the FOXO4 gene.

== Structure and function ==

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via Wikidata sitelinks · CC0

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