FOXO4
Sign in to saveAlso known as AFX, AFX1, MLLT7, forkhead box O4
Forkhead box protein O4 is a protein that in humans is encoded by the FOXO4 gene.
Gene data
FOXO4- Name
- forkhead box O4
- Type
- protein-coding
- Chromosome
- X
- Position
- 71,095,851–71,103,535 (+)
- Aliases
- AFX, AFX1, MLLT7
- Ensembl
- ENSG00000184481
- RefSeq RNA
- NM_001170931.2, NM_005938.4
- RefSeq protein
- NP_001164402.1, NP_005929.2
This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
forkhead box O4
- Symbol
- FOXO4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:71,095,839-71,103,535
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein MLLT7 PDB 1e17.png
Show 5 more facts
- HomoloGene ID
- 4342
- exact match
- identifiers.org/ncbigene/4303
- genomic end
- 71103532
- genomic start
- 71095851
- cytogenetic location
- Xq13.1
Sources (4)
via Wikidata · CC0
~4 min read
Article
9 sectionsContents
- Structure and function
- Clinical significance
- Associations with longevity
- Cancer
- Interactions
- See also
- References
- Further reading
- External links
Forkhead box protein O4 is a protein that in humans is encoded by the FOXO4 gene.
== Structure and function ==