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GeneQ15317282· pop 5· linked from 31 articles

Also known as BCSG1, SR, synuclein gamma

Gamma-synuclein is a protein that in humans is encoded by the SNCG gene.

Gene data

SNCG
Name
synuclein gamma
Type
protein-coding
Aliases
BCSG1, SR

This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010].

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Gene · Ensembl

synuclein gamma

Symbol
SNCG
Biotype
Protein coding
Organism
Homo sapiens
Location
10:86,955,753-86,963,264
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
2322
genomic end
86963258
genomic start
86958599
cytogenetic location
10q23.2
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Gamma-synuclein is a protein that in humans is encoded by the SNCG gene.

Synuclein-gamma is a member of the synuclein family of proteins, which are believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. Gamma-synuclein is a synuclein protein found primarily in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. It is also detected in the brain, ovarian tumors, and in the olfactory epithelium. Gamma-synuclein is the least conserved of the synuclein proteins.

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