sulfapyridine
Sign in to saveAlso known as Coccoclase, Piridazol, Sulfanilamidopyridine, Eubasin, N(1)-Pyridylsulfanilamide, 4-(2-Pyridinylsulfonyl)aniline, 2-Sulfapyridine, 4-Amino-N,2-pyridinylbenzenesulfonamide
Sulfapyridine (INN; also known as sulphapyridine) is a sulfanilamide antibacterial medication. At one time, it was commonly referred to as M&B 693. Sulfapyridine is no longer prescribed for treatment of infections in humans. However, it may be used to treat linear IgA disease and has use in veterinary medicine. It is a good antibacterial drug, but its water solubility is very pH dependent. Thus there is a risk of crystallization within the bladder or urethra, which could lead to pain or blockage. As with other sulfonamides, there is a significant risk of agranulocytosis, and this, rather than
Research
1,167 papers- Dapsone and sulfapyridine.Dermatologic clinics · 2001
- Dapsone and sulfapyridine.Clinics in dermatology · 1989
- Development of Novel Magneto-Biosensor for Sulfapyridine Detection.Biosensors · 2020
- Drug therapy: Sulfasalazine.The New England journal of medicine · 1975
- Mea culpa.Nature clinical practice. Gastroenterology & hepatology · 2008
via PubMed
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Encyclopedic overview
3 sectionsContents
- History
- Related medications
- References
Sulfapyridine (INN; also known as sulphapyridine) is a sulfanilamide antibacterial medication. At one time, it was commonly referred to as M&B 693. Sulfapyridine is no longer prescribed for treatment of infections in humans. However, it may be used to treat linear IgA disease and has use in veterinary medicine. It is a good antibacterial drug, but its water solubility is very pH dependent. Thus there is a risk of crystallization within the bladder or urethra, which could lead to pain or blockage. As with other sulfonamides, there is a significant risk of agranulocytosis, and this, rather than the development of resistance by bacteria, is the main reason for its decline in use.
==History==
Excerpted from Wikipedia’s “sulfapyridine” article, available under the CC BY-SA 4.0 licence.