thiabendazole

Also known as E233, MK-360, 2-(4-thiazolyl)-1H-benzimidazole, 2-(1,3-thiazol-4-yl)benzimidazole, 2-(thiazol-4-yl)benzimidazole, 4-(2-Benzimidazolyl)thiazole, TBDZ

Tiabendazole (INN, BAN), also known as thiabendazole (AAN, USAN) or TBZ and the trade names Mintezol, Tresaderm, and Arbotect, is a preservative, an antifungal agent, and an antiparasitic agent.

In the Vinony graph

Vinony's link graph records 128 inbound references to thiabendazole, and connects out to quinoline, anthelmintic and benzylamine.

It sits within the topics Antiparasitic agents, Benzimidazoles and Drugboxes which contain changes to verified fields.

Vinony links it to 24 Wikipedia language editions.

Chemical data

Formula: C10H7N3S
Molecular weight: 201.25 g/mol
IUPAC name: 4-(1H-benzimidazol-2-yl)-1,3-thiazole
SMILES: C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3
InChIKey: WJCNZQLZVWNLKY-UHFFFAOYSA-N
XLogP: 2.5
Polar surface area: 69.8 Å²
H-bond donors: 1
H-bond acceptors: 3
Formal charge: 0

via PubChem

Research

2,905 papers

Network toxicological and molecular docking to investigate the mechanisms of toxicity of agricultural chemical Thiabendazole.Chemosphere · 2024
Thiabendazole: toxicological, pharmacological and antifungal properties.Texas reports on biology and medicine · 1969
Thiabendazole inhibition of venom necrosis.The Journal of investigative dermatology · 1966
Developmental defects induced by thiabendazole are mediated via apoptosis, oxidative stress and alteration in PI3K/Akt and MAPK pathways in zebrafish.Environment international · 2023
[Thiabendazole, large-spectrum anthelmintic; its indications and its limitations: general review of 253 cases].Medecine tropicale : revue du Corps de sante colonial · 1969

via PubMed

Wikidata facts

Mass: 201.036

Show 5 more facts

chemical formula: C₁₀H₇N₃S
canonical SMILES: C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3
Commons category: Thiabendazole
defined daily dose: 3
MCN code: 2934.10.30

Sources (4)

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Encyclopedic overview

13 sections

Contents

Uses
Preservative
Parasiticide
Fungicide
Other
Research
Pharmacodynamics
Safety
Synthesis
Derivatives
See also
References
External links

Tiabendazole (INN, BAN), also known as thiabendazole (AAN, USAN) or TBZ and the trade names Mintezol, Tresaderm, and Arbotect, is a preservative, an antifungal agent, and an antiparasitic agent.

== Uses ==

Excerpted from Wikipedia’s “thiabendazole” article, available under the CC BY-SA 4.0 licence.