Structure via PubChem · Public domain (PubChem)
thioacetamide
Sign in to saveAlso known as Thioactamide, TAA, Thioacetimidic acid, Thiacetamide, Acetothioamide, methylthioamide, acetic acid thioamide, ethanethioamide
Thioacetamide is an organosulfur compound with the formula C2H5NS. This white crystalline solid is soluble in water and serves as a source of sulfide ions in the synthesis of organic and inorganic compounds. It is a prototypical thioamide.
Chemical data
- Formula
- C2H5NS
- Molecular weight
- 75.14 g/mol
- IUPAC name
- ethanethioamide
- SMILES
- CC(=S)N
- InChIKey
- YUKQRDCYNOVPGJ-UHFFFAOYSA-N
- XLogP
- -0.3
- Polar surface area
- 58.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 75.014
Show 4 more facts
- chemical formula
- C₂H₅NS
- canonical SMILES
- CC(=S)N
- melting point
- 112
- Commons category
- Thioacetamide
via Wikidata · CC0
~2 min read
Article
6 sectionsContents
- Research
- Coordination chemistry
- Preparation
- Structure
- Safety
- References
Thioacetamide is an organosulfur compound with the formula C2H5NS. This white crystalline solid is soluble in water and serves as a source of sulfide ions in the synthesis of organic and inorganic compounds. It is a prototypical thioamide.
==Research== Thioacetamide is known to induce acute or chronic liver disease (fibrosis and cirrhosis) in the experimental animal model. Its administration in rat induces hepatic encephalopathy, metabolic acidosis, increased levels of transaminases, abnormal coagulation, and centrilobular necrosis, which are the main features of the clinical chronic liver disease so thioacetamide can precisely replicate the initiation and progression of human liver disease in an experimental animal model.