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thozalinone
Sign in to saveThozalinone (USAN) (brand name Stimsen; former developmental code name CL-39808) is a psychostimulant that has been used as an antidepressant in Europe. It has also been trialed as an anorectic. Thozalinone is described as a "dopaminergic stimulant", and likely acts via inducing the release of dopamine and to a minimal extent norepinephrine; similar to analogue pemoline, it is reportedly devoid of abuse potential unlike most other dopaminergic psychostimulants.
In the Vinony graph
Within Vinony's link graph, thozalinone is referenced by 1,490 other articles, and connects out to D-methamphetamine, Anatomical Therapeutic Chemical Classification System and stimulant.
It is catalogued under topics including Aminorexes, Antidepressants and Chemical pages without DrugBank identifier.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C11H12N2O2
- Molecular weight
- 204.22 g/mol
- IUPAC name
- 2-(dimethylamino)-5-phenyl-1,3-oxazol-4-one
- SMILES
- CN(C)C1=NC(=O)C(O1)C2=CC=CC=C2
- InChIKey
- JJSHYECKYLDYAR-UHFFFAOYSA-N
- XLogP
- 1.5
- Polar surface area
- 41.9 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 204.09
Show 3 more facts
- chemical formula
- C₁₁H₁₂N₂O₂
- canonical SMILES
- CN(C)C1=NC(=O)C(O1)C2=CC=CC=C2
- Commons category
- Thozalinone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Synthesis
- Notes
- See also
- References
Thozalinone (USAN) (brand name Stimsen; former developmental code name CL-39808) is a psychostimulant that has been used as an antidepressant in Europe. It has also been trialed as an anorectic. Thozalinone is described as a "dopaminergic stimulant", and likely acts via inducing the release of dopamine and to a minimal extent norepinephrine; similar to analogue pemoline, it is reportedly devoid of abuse potential unlike most other dopaminergic psychostimulants.
==Synthesis== class=skin-invert-image|center|500px|thumb|Synthesis:
Excerpted from Wikipedia’s “thozalinone” article, available under the CC BY-SA 4.0 licence.