tiletamine
Sign in to saveTiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist. It is an arylcyclohexylamine chemically related to ketamine. Tiletamine hydrochloride exists as odorless white crystals.
Key facts
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 470610310
- Drug.IUPAC_name
- 2-Ethylamino-2-(2-thienyl)cyclohexanone
- Drug.image
- Tiletamine structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 175px
- Drug.image2
- Tiletamine-ball-and-stick-model.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 200px
- Drug.alt2
- (S)-tiletamine
- Drug.legal_AU
- S4
- Drug.legal_US
- Schedule III (when combined with Zolazepam)
- Drug.routes_of_administration
- IV, IM, SC, Other
- Drug.metabolism
- Liver
- Drug.excretion
- Kidneys
- Drug.index2_label
- HCl
- Drug.CAS_number
- 14176-49-9
- Drug.CAS_number2
- 14176-50-2
via Wikipedia infobox
Research
569 papers- Tiletamine-Zolazepam Use in Exotic Pets and Wildlife Anesthesia: A Narrative Review Towards Practical Guidelines.Animals : an open access journal from MDPI · 2026
- TILETAMINE-ZOLAZEPAM-XYLAZINE ANESTHESIA IN EX SITU BLACK-HANDED SPIDER MONKEYS (ATELES GEOFFROYI SSP.).Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians · 2024
- Dissociative anaesthesia in dogs and cats with use of tiletamine and zolazepam combination. What we already know about it.Polish journal of veterinary sciences · 2021
- Tiletamine-Zolazepam for Total Intravenous Anesthesia in Sheep.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
- Severe tremors induced by tiletamine e-cigarette and alcohol use: a case report.Frontiers in psychiatry · 2025
via PubMed
Wikidata facts
- Mass
- 223.103
Show 3 more facts
- chemical formula
- C₁₂H₁₇NOS
- canonical SMILES
- CCNC1(CCCCC1=O)C2=CC=CS2
- Commons category
- Tiletamine
Sources (2)
via Wikidata · CC0
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Article
4 sectionsContents
- Society and culture
- See also
- References
- External links
Tiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist. It is an arylcyclohexylamine chemically related to ketamine. Tiletamine hydrochloride exists as odorless white crystals.
It is used in veterinary medicine in the combination product Telazol (tiletamine/zolazepam, 50 mg/ml of each in 5 ml vial) as an injectable anesthetic for use in cats and dogs. It is sometimes used in combination with xylazine (Rompun) to chemically immobilize large mammals such as polar bears and wood bison. Telazol is the only commercially available tiletamine product in the United States. It is contraindicated in patients of an ASA score of III or greater and in animals with CNS signs, hyperthyroidism, cardiac disease, pancreatic or renal disease, pregnancy, glaucoma, or penetrating eye injuries.
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via Wikidata sitelinks · CC0