TRA2A

Also known as AWMS1, HSU53209, transformer 2 alpha homolog

Transformer-2 protein homolog alpha is a protein that in humans is encoded by the TRA2A gene.

In the Vinony graph

Within Vinony's link graph, TRA2A is referenced by 3 other articles, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 7.

Its subject is documented across 5 Wikipedia language editions.

Gene data

TRA2A

Name: transformer 2 alpha homolog
Type: protein-coding
Position: 23,504,780–23,532,041 (−)
Aliases: AWMS1, HSU53209
Ensembl: ENSG00000164548
RefSeq RNA: NM_001282757.2, NM_001282758.2, NM_001282759.2, NM_001362759.2, NM_001362760.2
RefSeq protein: NP_001269686.1, NP_001269687.1, NP_001269688.1, NP_001349688.1, NP_001349689.1

This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013].

Gene Ontology

Biological process

mRNA splicing, via spliceosome mRNA splicing, via spliceosome

Molecular function

nucleic acid binding RNA binding RNA binding mRNA binding protein binding

Cellular component

nucleus nucleus nucleoplasm spliceosomal complex nucleolus

Pathways

Spliceosome - Homo sapiens (human)

via MyGene.info

Gene · Ensembl

transformer 2 alpha homolog

Symbol: TRA2A
Biotype: Protein coding
Organism: Homo sapiens
Location: 7:23,504,780-23,532,041
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 40866
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/29896
genomic end: 23571660
genomic start: 23544399
chromosome: human chromosome 7
cytogenetic location: 7p15.3

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Transformer-2 protein homolog alpha is a protein that in humans is encoded by the TRA2A gene.

This gene is a member of the transformer 2 homolog family and encodes a protein with two RS domains and an RRM (RNA recognition motif) domain. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Several alternatively spliced transcript variants of this gene have been described; however, the full-length nature of some of these variants has not been determined.

Excerpted from Wikipedia’s “TRA2A” article, available under the CC BY-SA 4.0 licence.