TRA2B
Sign in to saveAlso known as Htra2-beta, PPP1R156, SFRS10, SRFS10, TRA2-BETA, TRAN2B, transformer 2 beta homolog (Drosophila), transformer 2 beta homolog
Transformer-2 protein homolog beta, also known as TRA2B previously known as splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) (SFRS10), is a protein that in humans is encoded by the TRA2B gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to TRA2B, and connects out to PubMed, human chromosome 3 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 3.
Vinony links it to 6 Wikipedia language editions.
Gene data
TRA2B- Name
- transformer 2 beta homolog
- Type
- protein-coding
- Position
- 185,914,558–185,938,103 (−)
- Aliases
- Htra2-beta, PPP1R156, RAMELN, SFRS10, SRFS10, TRA2-BETA, TRAN2B
- Ensembl
- ENSG00000136527
- RefSeq RNA
- NM_001243879.2, NM_004593.3, XM_047448717.1, XM_054347538.1
- RefSeq protein
- NP_001230808.1, NP_004584.1, XP_047304673.1, XP_054203513.1
This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
transformer 2 beta homolog
- Symbol
- TRA2B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:185,914,558-185,938,103
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SFRS10 PDB 2cqc.png
Show 7 more facts
- HomoloGene ID
- 20965
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6434
- genomic end
- 185938103
- genomic start
- 185914558
- chromosome
- human chromosome 3
- cytogenetic location
- 3q27.2
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Transformer-2 protein homolog beta, also known as TRA2B previously known as splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) (SFRS10), is a protein that in humans is encoded by the TRA2B gene.
TRA2B contains a poison exon whose inclusion is autoregulated by TRA2B protein. Proper regulation of poison exon inclusion in TRA2B is important for T cell fate.
Excerpted from Wikipedia’s “TRA2B” article, available under the CC BY-SA 4.0 licence.