TRA2B
Sign in to saveAlso known as Htra2-beta, PPP1R156, SFRS10, SRFS10, TRA2-BETA, TRAN2B, transformer 2 beta homolog (Drosophila), transformer 2 beta homolog
Transformer-2 protein homolog beta, also known as TRA2B previously known as splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) (SFRS10), is a protein that in humans is encoded by the TRA2B gene.
Gene data
TRA2B- Name
- transformer 2 beta homolog
- Type
- protein-coding
- Aliases
- Htra2-beta, PPP1R156, RAMELN, SFRS10, SRFS10, TRA2-BETA, TRAN2B
This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011].
via MyGene.info
Gene · Ensembl
transformer 2 beta homolog
- Symbol
- TRA2B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:185,914,558-185,938,103
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein SFRS10 PDB 2cqc.png
Show 5 more facts
- HomoloGene ID
- 20965
- exact match
- identifiers.org/ncbigene/6434
- genomic end
- 185938103
- genomic start
- 185914558
- cytogenetic location
- 3q27.2
Sources (4)
via Wikidata · CC0
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- Further reading
Transformer-2 protein homolog beta, also known as TRA2B previously known as splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) (SFRS10), is a protein that in humans is encoded by the TRA2B gene.
TRA2B contains a poison exon whose inclusion is autoregulated by TRA2B protein. Proper regulation of poison exon inclusion in TRA2B is important for T cell fate.