Also known as MAGE-d3, MAGED3, trophinin
Trophinin is a protein that in humans is encoded by the TRO gene.
Gene data
TRO- Name
- trophinin
- Type
- protein-coding
- Chromosome
- X
- Aliases
- MAGE-d3, MAGED3
This gene encodes a membrane protein that mediates cell adhesion between trophoblastic cells and the epithelial cells of the endometrium. The encoded protein participates in cell signalling during embryo implantation, and may also be involved in cancer formation. This gene is located near several other closely related genes on chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].
via MyGene.info
Gene · Ensembl
trophinin
- Symbol
- TRO
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:54,920,462-54,931,436
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 75113
- exact match
- identifiers.org/ncbigene/7216
- genomic end
- 54957864
- genomic start
- 54946895
- cytogenetic location
- Xp11.21
Sources (4)
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- Further reading
Trophinin is a protein that in humans is encoded by the TRO gene.
This gene encodes a membrane protein that mediates apical cell adhesion between trophoblastic cells and luminal epithelial cells of the endometrium and is implicated in the initial attachment during the process of embryo implantation. This gene is related to the MAGED gene family by sequence similarity and chromosome location. Multiple alternatively spliced transcript variants have been found for this gene; however, the full-length nature of some variants has not been defined.