YM348
Sign in to saveAlso known as YM-348
YM-348 is an indazolethylamine derivative drug which acts as a potent and selective 5-HT2C receptor agonist, with an EC50 of 1nM and 15x selectivity over 5-HT2A, although it only has moderate selectivity of 3x over the closely related 5-HT2B receptor. It has thermogenic and anorectic effects in animal studies, making it potentially useful for the treatment of obesity.
Wikidata facts
- Mass
- 243.137162
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- chemical formula
- C₁₄H₁₇N₃O
- isomeric SMILES
- CCC1=CC2=C(O1)C=CC3=C2N(N=C3)C[C@H](C)N
- canonical SMILES
- CCC1=CC2=C(O1)C=CC3=C2N(N=C3)CC(C)N
- Commons category
- YM-348
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YM-348 is an indazolethylamine derivative drug which acts as a potent and selective 5-HT2C receptor agonist, with an EC50 of 1nM and 15x selectivity over 5-HT2A, although it only has moderate selectivity of 3x over the closely related 5-HT2B receptor. It has thermogenic and anorectic effects in animal studies, making it potentially useful for the treatment of obesity.
== See also == Indazolethylamine Substituted tryptamine § Related compounds AL-34662 AL-38022A O-Methyl-AL-34662 Ro60-0175 VER-3323