Structure via PubChem · Public domain (PubChem)
4-hydroxytestosterone
Sign in to saveAlso known as 4ohtestosterone, 7alpha-Hydroxytestosterone, 4,17beta-Dihydroxy-4-androstene-3-one, 4-Androstene-7alpha-17beta-diol-3-one
4-Hydroxytestosterone (4-OHT), also known as 4,17β-dihydroxyandrost-4-en-3-one, is a synthetic anabolic-androgenic steroid (AAS) and a derivative of testosterone that was never marketed. It was first patented by G.D. Searle & Company in 1955 and is testosterone with a hydroxy group at the four position. 4-OHT has moderate anabolic, mild androgenic, and anti-aromatase properties and is similar to the steroid clostebol (4-chlorotestosterone).
In the Vinony graph
Within Vinony's link graph, 4-hydroxytestosterone is referenced by 521 other articles, and connects out to androgen, androstenedione and abiraterone acetate.
It is catalogued under topics including Androgens, Androstanes and Aromatase inhibitors.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C19H28O3
- Molecular weight
- 304.4 g/mol
- IUPAC name
- (8R,9S,10R,13S,14S,17S)-4,17-dihydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
- SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C(C(=O)CC[C@]34C)O
- InChIKey
- BQOIJSIMMIDHMO-FBPKJDBXSA-N
- XLogP
- 3.2
- Polar surface area
- 57.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- steroid
- Mass
- 304.204
Show 4 more facts
- Commons category
- 4-Hydroxytestosterone
- chemical formula
- C₁₉H₂₈O₃
- canonical SMILES
- CC12CCC3C(C1CCC2O)CCC4=C(C(=O)CCC34C)O
- isomeric SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C(C(=O)CC[C@]34C)O
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
4-Hydroxytestosterone (4-OHT), also known as 4,17β-dihydroxyandrost-4-en-3-one, is a synthetic anabolic-androgenic steroid (AAS) and a derivative of testosterone that was never marketed. It was first patented by G.D. Searle & Company in 1955 and is testosterone with a hydroxy group at the four position. 4-OHT has moderate anabolic, mild androgenic, and anti-aromatase properties and is similar to the steroid clostebol (4-chlorotestosterone).
==See also== 4-Androstene-3,6,17-trione Androstenedione Enestebol Formestane 11β-Hydroxytestosterone
Excerpted from Wikipedia’s “4-hydroxytestosterone” article, available under the CC BY-SA 4.0 licence.