4-ヒドロキシテストステロン

Also known as 4ohtestosterone, 7alpha-Hydroxytestosterone, 4,17beta-Dihydroxy-4-androstene-3-one, 4-Hydroxytestosterone, 4-Androstene-7alpha-17beta-diol-3-one

4-Hydroxytestosterone (4-OHT), also known as 4,17β-dihydroxyandrost-4-en-3-one, is a synthetic anabolic-androgenic steroid (AAS) and a derivative of testosterone that was never marketed. It was first patented by G.D. Searle & Company in 1955 and is testosterone with a hydroxy group at the four position. 4-OHT has moderate anabolic, mild androgenic, and anti-aromatase properties and is similar to the steroid clostebol (4-chlorotestosterone).

In the Vinony graph

Within Vinony's link graph, 4-ヒドロキシテストステロン is referenced by 521 other articles, and connects out to androgen, androstenedione and abiraterone acetate.

It is catalogued under topics including Androgens, Androstanes and Aromatase inhibitors.

Its subject is documented across 6 Wikipedia language editions.

Chemical data

Formula: C19H28O3
Molecular weight: 304.4 g/mol
IUPAC name: (8R,9S,10R,13S,14S,17S)-4,17-dihydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C(C(=O)CC[C@]34C)O
InChIKey: BQOIJSIMMIDHMO-FBPKJDBXSA-N
XLogP: 3.2
Polar surface area: 57.5 Å²
H-bond donors: 2
H-bond acceptors: 3
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: steroid
Mass: 304.204

Show 4 more facts

Commons category: 4-Hydroxytestosterone
chemical formula: C₁₉H₂₈O₃
canonical SMILES: CC12CCC3C(C1CCC2O)CCC4=C(C(=O)CCC34C)O
isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C(C(=O)CC[C@]34C)O

Sources (3)

via Wikidata · CC0

Article · 日本語

4-ヒドロキシテストステロン(4-Hydroxytestosterone)は、アナボリックステロイドの1つである。4位がヒドロキシ基に置換したテストステロンである。1955年にサールによって初めて特許が取られた。4-ヒドロキシテストステロンは、穏やかに同化され、軽度のアンドロゲン作用を持ち、反芳香性があり、ステロイドのクロステボルに似る。

Abstract from DBpedia / Wikipedia · CC BY-SA