ACTG2

Also known as ACT, ACTA3, ACTE, ACTL3, ACTSG, VSCM, actin, gamma 2, smooth muscle, enteric, actin gamma 2, smooth muscle

Actin, gamma-enteric smooth muscle is a protein that in humans is encoded by the ACTG2 gene.

Gene data

ACTG2

Name: actin gamma 2, smooth muscle
Type: protein-coding
Aliases: ACT, ACTA3, ACTE, ACTL3, ACTSG, MMIHS5, VSCM, VSCM1

Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010].

via MyGene.info

Gene · Ensembl

actin gamma 2, smooth muscle

Symbol: ACTG2
Biotype: Protein coding
Organism: Homo sapiens
Location: 2:73,892,232-73,919,865
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: PBB Protein ACTA1 image.jpg

Show 5 more facts

HomoloGene ID: 123845
exact match: identifiers.org/ncbigene/72
genomic end: 74146992
genomic start: 74119441
cytogenetic location: 2p13.1

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Actin, gamma-enteric smooth muscle is a protein that in humans is encoded by the ACTG2 gene.

Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues.