AGXT2
Sign in to saveAlso known as AGT2, DAIBAT, alanine--glyoxylate aminotransferase 2, BAIBA
The human AGXT2 gene encodes the protein Alanine—glyoxylate aminotransferase 2.
In the Vinony graph
Within Vinony's link graph, AGXT2 is referenced by 2 other articles, and connects out to PubMed, human chromosome 5 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 5.
Its subject is documented across 5 Wikipedia language editions.
Gene data
AGXT2- Name
- alanine--glyoxylate aminotransferase 2
- Type
- protein-coding
- Position
- 34,997,427–35,048,240 (−)
- Aliases
- AGT2, BAIBA, DAIBAT
- Ensembl
- ENSG00000113492
- RefSeq RNA
- NM_001306173.2, NM_001438050.1, NM_001438583.1, NM_001438584.1, NM_001438585.1
- RefSeq protein
- NP_001293102.1, NP_001424979.1, NP_001425512.1, NP_001425513.1, NP_001425514.1
The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
alanine--glyoxylate aminotransferase 2
- Symbol
- AGXT2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:34,997,427-35,048,240
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 12887
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/64902
- genomic end
- 35048198
- genomic start
- 34998206
- chromosome
- human chromosome 5
- cytogenetic location
- 5p13.2
- expressed in
- muscle tissue
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
The human AGXT2 gene encodes the protein Alanine—glyoxylate aminotransferase 2.
== Function ==
Excerpted from Wikipedia’s “AGXT2” article, available under the CC BY-SA 4.0 licence.