Also known as OS3, PLAP-1, PLAP1, SLRR1C, asporin, Asporin
Asporin is a protein that in humans is encoded by the ASPN gene.
This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants.[provided by RefSeq, Jul 2014].
via MyGene.info
Asporin is a protein that in humans is encoded by the ASPN gene.
== Function ==
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).