ASPN
Sign in to saveAlso known as OS3, PLAP-1, PLAP1, SLRR1C, asporin, Asporin
Asporin is a protein that in humans is encoded by the ASPN gene.
Gene data
ASPN- Name
- asporin
- Type
- protein-coding
- Aliases
- OS3, PLAP-1, PLAP1, SLRR1C
This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants.[provided by RefSeq, Jul 2014].
via MyGene.info
Wikidata facts
Show 3 more facts
- HomoloGene ID
- 32357
- exact match
- identifiers.org/ncbigene/54829
- cytogenetic location
- 9q22.31
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- References
- External links
- Further reading
Asporin is a protein that in humans is encoded by the ASPN gene.
== Function ==