ATG12
Sign in to saveAlso known as APG12, APG12L, FBR93, HAPG12, autophagy related 12
Autophagy related 12 is a protein that in humans is encoded by the ATG12 gene.
In the Vinony graph
Vinony's link graph records 119 inbound references to ATG12, and connects out to PubMed, human chromosome 5 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 5.
Vinony links it to 7 Wikipedia language editions.
Gene data
ATG12- Name
- autophagy related 12
- Type
- protein-coding
- Position
- 115,828,182–115,842,534 (−)
- Aliases
- APG12, APG12L, FBR93, HAPG12
- Ensembl
- ENSG00000145782
- RefSeq RNA
- NM_001277783.2, NM_004707.4, NR_033362.2, NR_033363.2, NR_073603.2
- RefSeq protein
- NP_001264712.1, NP_004698.3
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
autophagy related 12
- Symbol
- ATG12
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:115,828,182-115,842,534
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 37953
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9140
- genomic end
- 115841837
- genomic start
- 115163893
- expressed in
- visceral pleura
- chromosome
- human chromosome 5
- cytogenetic location
- 5q22.3
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Autophagy related 12 is a protein that in humans is encoded by the ATG12 gene.
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998).[supplied by OMIM]
Excerpted from Wikipedia’s “ATG12” article, available under the CC BY-SA 4.0 licence.