ADGRD1
Sign in to saveAlso known as PGR25, GPR133, adhesion G protein-coupled receptor D1
Probable G-protein coupled receptor 133 is a protein that in humans is encoded by the GPR133 gene.
In the Vinony graph
Vinony's link graph records 486 inbound references to ADGRD1, and connects out to PubMed, Ensembl genome database project and cell surface receptor.
It is catalogued under topics including Genes on human chromosome 12 and G protein-coupled receptors.
Vinony links it to 5 Wikipedia language editions.
Gene data
ADGRD1- Name
- adhesion G protein-coupled receptor D1
- Type
- protein-coding
- Position
- 130,953,035–131,142,466 (+)
- Aliases
- GPR133, PGR25
- Ensembl
- ENSG00000111452
- RefSeq RNA
- NM_001330497.2, NM_198827.5, XM_005253566.2, XM_011538204.2, XM_011538205.2
- RefSeq protein
- NP_001317426.1, NP_942122.2, XP_005253623.1, XP_011536506.1, XP_011536507.1
The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]).[supplied by OMIM, Nov 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
adhesion G protein-coupled receptor D1
- Symbol
- ADGRD1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:130,953,035-131,142,466
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 34616
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/283383
- genomic end
- 131626014
- genomic start
- 131438452
- chromosome
- human chromosome 12
- cytogenetic location
- 12q24.33
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Probable G-protein coupled receptor 133 is a protein that in humans is encoded by the GPR133 gene.
This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
Excerpted from Wikipedia’s “ADGRD1” article, available under the CC BY-SA 4.0 licence.