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GeneQ18054116· pop 5· linked from 486 articles

Also known as PGR25, GPR133, adhesion G protein-coupled receptor D1

Probable G-protein coupled receptor 133 is a protein that in humans is encoded by the GPR133 gene.

Gene data

ADGRD1
Name
adhesion G protein-coupled receptor D1
Type
protein-coding
Aliases
GPR133, PGR25

The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]).[supplied by OMIM, Nov 2010].

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Gene · Ensembl

adhesion G protein-coupled receptor D1

Symbol
ADGRD1
Biotype
Protein coding
Organism
Homo sapiens
Location
12:130,953,035-131,142,466
Strand
Forward (+)
Assembly
GRCh38
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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
34616
genomic end
131626014
genomic start
131438452
cytogenetic location
12q24.33
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Contents
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Probable G-protein coupled receptor 133 is a protein that in humans is encoded by the GPR133 gene.

This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

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