GPR150
Sign in to saveAlso known as PGR11, G protein-coupled receptor 150
Probable G-protein coupled receptor 150 is a protein that in humans is encoded by the GPR150 gene.
Gene data
GPR150- Name
- G protein-coupled receptor 150
- Type
- protein-coding
- Aliases
- PGR11
This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017].
via MyGene.info
Gene · Ensembl
G protein-coupled receptor 150
- Symbol
- GPR150
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:95,620,087-95,622,142
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 18457
- exact match
- identifiers.org/ncbigene/285601
- genomic end
- 94957846
- genomic start
- 95620087
- cytogenetic location
- 5q15
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Probable G-protein coupled receptor 150 is a protein that in humans is encoded by the GPR150 gene.
==References==