GPR150

Name

G protein-coupled receptor 150

Type

protein-coding

Position

95,620,087–95,622,142 (+)

Aliases

PGR11

Ensembl

ENSG00000178015

RefSeq RNA

NM_199243.3

RefSeq protein

NP_954713.1

This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017].

via MyGene.info

Gene · Ensembl

G protein-coupled receptor 150

Symbol

GPR150

Biotype

Protein coding

Organism

Homo sapiens

Location

5:95,620,087-95,622,142

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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