GPR153

Also known as PGR1, G protein-coupled receptor 153

Probable G-protein coupled receptor 153 is a protein that in humans is encoded by the GPR153 gene.

In the Vinony graph

Vinony's link graph records 485 inbound references to GPR153, and connects out to PubMed, Ensembl genome database project and cell surface receptor.

It is catalogued under topics including Genes on human chromosome 1 and G protein-coupled receptors.

Vinony links it to 5 Wikipedia language editions.

Gene data

GPR153

Name: G protein-coupled receptor 153
Type: protein-coding
Aliases: PGR1

This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells. [provided by RefSeq, Feb 2017].

via MyGene.info