Structure via PubChem · Public domain (PubChem)
atiprosin
Sign in to saveAtiprosin (developmental code name AY-28,228) is an antihypertensive agent which acts as a selective α1-adrenergic receptor antagonist. It also possesses some antihistamine activity, though it is some 15-fold weaker in this regard than as an alpha blocker. It was never marketed.
In the Vinony graph
Within Vinony's link graph, atiprosin is referenced by 657 other articles, and connects out to propranolol, histamine antagonist and atenolol.
It is catalogued under topics including Abandoned drugs, Alpha-1 blockers and Antihistamines.
Its subject is documented across 4 Wikipedia language editions.
Chemical data
- Formula
- C20H29N3
- Molecular weight
- 311.5 g/mol
- IUPAC name
- (2S,7R)-3-ethyl-17-methyl-6-propan-2-yl-3,6,10-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),11,13,15-tetraene
- SMILES
- CCN1CCN([C@H]2[C@H]1C3=C(C4=CC=CC=C4N3CC2)C)C(C)C
- InChIKey
- WXNVFYIBELASJW-QUCCMNQESA-N
- XLogP
- 3.4
- Polar surface area
- 11.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 311.236148
Show 4 more facts
- chemical formula
- C₂₀H₂₉N₃
- canonical SMILES
- CCN1CCN(C2C1C3=C(C4=CC=CC=C4N3CC2)C)C(C)C
- isomeric SMILES
- CCN1CCN([C@H]2[C@H]1C3=C(C4=CC=CC=C4N3CC2)C)C(C)C
- Commons category
- Atiprosin
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
Atiprosin (developmental code name AY-28,228) is an antihypertensive agent which acts as a selective α1-adrenergic receptor antagonist. It also possesses some antihistamine activity, though it is some 15-fold weaker in this regard than as an alpha blocker. It was never marketed.
==See also== Prazosin Ketanserin
Excerpted from Wikipedia’s “atiprosin” article, available under the CC BY-SA 4.0 licence.