CADPS

Also known as CADPS1, CAPS, CAPS1, UNC-31, Ca2+ dependent secretion activator, calcium dependent secretion activator

Calcium-dependent secretion activator 1 is a protein that in humans is encoded by the CADPS gene.

In the Vinony graph

Vinony's link graph records 5 inbound references to CADPS, and connects out to PubMed, human chromosome 3 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 3.

Vinony links it to 5 Wikipedia language editions.

Gene data

CADPS

Name: calcium dependent secretion activator
Type: protein-coding
Position: 62,398,346–62,875,563 (−)
Aliases: CADPS1, CAPS, CAPS1, UNC-31
Ensembl: ENSG00000163618
RefSeq RNA: NM_001437891.1, NM_001438347.1, NM_001438348.1, NM_001438349.1, NM_001438350.1
RefSeq protein: NP_001424820.1, NP_001425276.1, NP_001425277.1, NP_001425278.1, NP_001425279.1

This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008].

Gene Ontology

Biological process

exocytosis exocytosis synaptic vesicle exocytosis positive regulation of exocytosis dense core granule exocytosis

Molecular function

protein binding protein kinase binding

Cellular component

cytosol synapse synapse presynapse glutamatergic synapse neuronal dense core vesicle membrane

via MyGene.info

Gene · Ensembl

calcium dependent secretion activator

Symbol: CADPS
Biotype: Protein coding
Organism: Homo sapiens
Location: 3:62,398,346-62,875,563
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein CADPS PDB 1wi1.png

Show 8 more facts

HomoloGene ID: 2755
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/8618
genomic end: 62875416
genomic start: 62384022
expressed in: postcentral gyrus
chromosome: human chromosome 3
cytogenetic location: 3p14.2

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

3 sections

Contents

References
External links
Further reading

Calcium-dependent secretion activator 1 is a protein that in humans is encoded by the CADPS gene.

CADPS encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. CADPS acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.

Excerpted from Wikipedia’s “CADPS” article, available under the CC BY-SA 4.0 licence.