CALCR

Also known as CRT, CT-R, CTR, CTR1, calcitonin receptor

protein-coding gene in the species Homo sapiens

Gene data

CALCR

Name: calcitonin receptor
Type: protein-coding
Position: 93,424,486–93,575,738 (−)
Aliases: CRT, CT-R, CTR, CTR1
Ensembl: ENSG00000004948
RefSeq RNA: NM_001164737.3, NM_001164738.2, NM_001742.4
RefSeq protein: NP_001158209.2, NP_001158210.1, NP_001733.1

This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].