CCKBR
Sign in to saveAlso known as CCK-B, CCK2R, GASR, cholecystokinin B receptor
protein-coding gene in the species Homo sapiens
Gene data
CCKBR- Name
- cholecystokinin B receptor
- Type
- protein-coding
- Position
- 6,259,806–6,272,127 (+)
- Aliases
- CCK-2R, CCK-B, CCK2R, GASR
- Ensembl
- ENSG00000110148
- RefSeq RNA
- NM_001318029.2, NM_001363552.2, NM_176875.4
- RefSeq protein
- NP_001304958.1, NP_001350481.1, NP_795344.1
This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cholecystokinin B receptor
- Symbol
- CCKBR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:6,259,698-6,272,127
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Cholecystokinin B receptor structure from the AlphaFold database with truncated terminal domains and ICL3.png
Show 5 more facts
- HomoloGene ID
- 7258
- exact match
- identifiers.org/ncbigene/887
- genomic end
- 6293357
- genomic start
- 6259806
- cytogenetic location
- 11p15.4
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