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GeneQ5104299· pop 7· linked from 512 articles

Also known as CCK-B, CCK2R, GASR, cholecystokinin B receptor

protein-coding gene in the species Homo sapiens

Gene data

CCKBR
Name
cholecystokinin B receptor
Type
protein-coding
Position
6,259,806–6,272,127 (+)
Aliases
CCK-2R, CCK-B, CCK2R, GASR
RefSeq RNA
NM_001318029.2, NM_001363552.2, NM_176875.4
RefSeq protein
NP_001304958.1, NP_001350481.1, NP_795344.1

This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015].

via MyGene.info

Gene · Ensembl

cholecystokinin B receptor

Symbol
CCKBR
Biotype
Protein coding
Organism
Homo sapiens
Location
11:6,259,698-6,272,127
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Cholecystokinin B receptor structure from the AlphaFold database with truncated terminal domains and ICL3.png
Show 5 more facts
HomoloGene ID
7258
genomic end
6293357
genomic start
6259806
cytogenetic location
11p15.4
Sources (4)

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Available in 7 languages

via Wikidata sitelinks · CC0

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