CCKBR

Name

cholecystokinin B receptor

Type

protein-coding

Position

6,259,806–6,272,127 (+)

Aliases

CCK-2R, CCK-B, CCK2R, GASR

Ensembl

ENSG00000110148

RefSeq RNA

NM_001318029.2, NM_001363552.2, NM_176875.4

RefSeq protein

NP_001304958.1, NP_001350481.1, NP_795344.1

This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015].