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GeneQ17916068· pop 5· linked from 488 articles

Also known as CDHF11, EGFL1, FMI1, HFMI1, MEGF2, RESDA1, ADGRC3, cadherin EGF LAG seven-pass G-type receptor 3

Cadherin EGF LAG seven-pass G-type receptor 3 is a protein that in humans is encoded by the CELSR3 gene.

Gene data

CELSR3
Name
cadherin EGF LAG seven-pass G-type receptor 3
Type
protein-coding
Position
48,636,463–48,662,886 (−)
Aliases
ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2, RESDA1
RefSeq RNA
NM_001407.3
RefSeq protein
NP_001398.2

This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013].

Pathways

via MyGene.info

Gene · Ensembl

cadherin EGF LAG seven-pass G-type receptor 3

Symbol
CELSR3
Biotype
Protein coding
Organism
Homo sapiens
Location
3:48,636,463-48,662,886
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
1077
found in taxon
Homo sapiens
genomic end
48662886
genomic start
48636463
cytogenetic location
3p21.31
Sources (4)

via Wikidata · CC0

Available in 5 languages

via Wikidata sitelinks · CC0