clofilium
Sign in to saveClofilium is an antiarrhythmic agent.
Research
228 papers- Efficient clofilium tosylate-mediated rescue of POLG-related disease phenotypes in zebrafish.Cell death & disease · 2021
- Iberiotoxin and clofilium regulate hyperactivation, acrosome reaction, and ion homeostasis synergistically during human sperm capacitation.Molecular reproduction and development · 2023
- Slo3 K+ channel blocker clofilium extends bull and mouse sperm-fertilizing competence.Reproduction (Cambridge, England) · 2018
- Clofilium, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3.Cancer letters · 1999
- Inhibitory effects of clofilium on membrane currents associated with Ca channels, NMDA receptor channels and Na+, K+-ATPase in cortical neurons.Pharmacology · 2005
via PubMed
Wikidata facts
- Mass
- 338.261453
Show 2 more facts
- canonical SMILES
- CCCCCCC[N+](CC)(CC)CCCCC1=CC=C(C=C1)Cl
- chemical formula
- C₂₁H₃₇ClN⁺
Sources (2)
via Wikidata · CC0
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Article
Clofilium is an antiarrhythmic agent.
Category:Quaternary ammonium compounds Category:Antiarrhythmic agents Category:4-Chlorophenyl compounds
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chemical formula
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organic compound
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simplified molecular input line entry specification
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Q2311683
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antiarrhythmic agent
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standard state
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