chlophedianol

Also known as SL-501, clofedanol

Clofedanol (INN) or chlophedianol (BAN), sold under the brand name Ninjacof among others, is a centrally acting cough suppressant used in the treatment of dry cough. Clofedanol has local anesthetic, antispasmodic, and antihistamine properties, and may have anticholinergic effects at high doses.

In the Vinony graph

Within Vinony's link graph, chlophedianol is referenced by 91 other articles, and connects out to antitussive, Japan and Canada.

It is catalogued under topics including 2-Chlorophenyl compounds, Antitussives and Dimethylamino compounds.

Its subject is documented across 6 Wikipedia language editions.

Chemical data

Formula: C17H20ClNO
Molecular weight: 289.8 g/mol
IUPAC name: 1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol
SMILES: CN(C)CCC(C1=CC=CC=C1)(C2=CC=CC=C2Cl)O
InChIKey: WRCHFMBCVFFYEQ-UHFFFAOYSA-N
XLogP: 3.6
Polar surface area: 23.5 Å²
H-bond donors: 1
H-bond acceptors: 2
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1982
Admin. routes: oral
Indications: Cough

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 289.123342
Has use: medication

Show 5 more facts

chemical formula: C₁₇H₂₀ClNO
World Health Organisation international non-proprietary name: clofedanol
canonical SMILES: CN(C)CCC(C1=CC=CC=C1)(C2=CC=CC=C2Cl)O
defined daily dose: 60
Commons category: Clofedanol

Sources (3)

via Wikidata · CC0

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Encyclopedic overview

5 sections

Contents

Side effects
Pharmacology
Society and culture
See also
References

==Side effects== Adverse effects may include irritability, drowsiness, nightmares, vertigo, nausea or vomiting, visual disturbances or hallucinations, and urticaria. There are potential interactions with other anticholinergics, CNS depressants, and alcohol.

Excerpted from Wikipedia’s “chlophedianol” article, available under the CC BY-SA 4.0 licence.