Structure via PubChem · Public domain (PubChem)
codoxime
Sign in to saveCodoxime (Codossima) is an opiate analogue that is a derivative of hydrocodone, where the 6-ketone group has been replaced by carboxymethyloxime. It has primarily antitussive effects and was found to have moderate potential to cause dependence in animal studies.
In the Vinony graph
Within Vinony's link graph, codoxime is referenced by 12 other articles, and connects out to (+)-catechin, butorphanol and opium.
It sits within the topics 4,5-Epoxymorphinans, Antitussives and Catechol ethers.
Its subject is documented across 6 Wikipedia language editions.
Chemical data
- Formula
- C20H24N2O5
- Molecular weight
- 372.4 g/mol
- IUPAC name
- 2-[(E)-[(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene]amino]oxyacetic acid
- SMILES
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3/C(=N/OCC(=O)O)/CC4
- InChIKey
- WKJYCUVUZIIMJA-OIBQYEROSA-N
- XLogP
- 0.1
- Polar surface area
- 80.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 372.168522
Show 3 more facts
- chemical formula
- C₂₀H₂₄N₂O₅
- canonical SMILES
- CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(=NOCC(=O)O)CC4
- isomeric SMILES
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3/C(=N/OCC(=O)O)/CC4
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Codoxime (Codossima) is an opiate analogue that is a derivative of hydrocodone, where the 6-ketone group has been replaced by carboxymethyloxime. It has primarily antitussive effects and was found to have moderate potential to cause dependence in animal studies.
==References==
Excerpted from Wikipedia’s “codoxime” article, available under the CC BY-SA 4.0 licence.