COPA
Sign in to saveAlso known as HEP-COP, AILJK, coatomer protein complex subunit alpha, alpha-COP, COPI coat complex subunit alpha
gène de l'espèce Homo sapiens
In the Vinony graph
Within Vinony's link graph, COPA is referenced by 82 other articles, and connects out to PubMed, Ensembl genome database project and protein.
It is catalogued under the topic Human genes.
Its subject is documented across 5 Wikipedia language editions.
Gene data
COPA- Name
- coat protein complex I subunit alpha
- Type
- protein-coding
- Position
- 160,288,580–160,343,566 (−)
- Aliases
- AIAISD, AIAISD1, AILJK, HEP-COP, alpha-COP
- Ensembl
- ENSG00000122218
- RefSeq RNA
- NM_001098398.2, NM_004371.4
- RefSeq protein
- NP_001091868.1, NP_004362.2
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
- Instance of
- gene
- Image
- The structure of the COPI coat linkage I - Coatomer subunit alpha (2) 5NZT.png
Show 5 more facts
- HomoloGene ID
- 3218
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1314
- cytogenetic location
- 1q23.2
- expressed in
- cardia
Sources (4)
via Wikidata · CC0