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CP-532,903
Sign in to saveCP-532,903 is a selective adenosine A3 subtype receptor agonist. It has antiinflammatory effects and has been shown to reduce superoxide generation in damaged tissues, and protects against tissue damage following myocardial ischemia, mediated via an interaction with ATP-sensitive potassium channels.
Chemical data
- Formula
- C18H19Cl2N7O3
- Molecular weight
- 452.3 g/mol
- IUPAC name
- (2S,3S,4R,5R)-3-amino-5-[6-[(2,5-dichlorophenyl)methylamino]purin-9-yl]-4-hydroxy-N-methyloxolane-2-carboxamide
- SMILES
- CNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)NCC4=C(C=CC(=C4)Cl)Cl)O)N
- InChIKey
- WFRYPIJMCFQCGT-MHMFGPJMSA-N
- XLogP
- 1.3
- Polar surface area
- 140 Ų
- H-bond donors
- 4
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 451.092643
Show 3 more facts
- chemical formula
- C₁₈H₁₉Cl₂N₇O₃
- isomeric SMILES
- CNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3NCC4=C(C=CC(=C4)Cl)Cl)O)N
- canonical SMILES
- CNC(=O)C1C(C(C(O1)N2C=NC3=C2N=CN=C3NCC4=C(C=CC(=C4)Cl)Cl)O)N
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
{{chembox | verifiedrevid = 417543408 | ImageFile=CP-532,903.svg | ImageSize=200px | IUPACName=6-{[(2,5-Dichlorophenyl)methyl]amino}-9H-purin-9-yl 3-amino-3-deoxy-N-methyl-β-D-ribofuranosiduronamide | SystematicName=(2S,3S,4R,5R)-3-Amino-5-(6-{[(2,5-dichlorophenyl)methyl]amino}-9H-purin-9-yl)-4-hydroxy-N5-methyloxolane-2-carboxamide | OtherNames=CP-532,903 |Section1= |Section2= |Section3= }}
CP-532,903 is a selective adenosine A3 subtype receptor agonist. It has antiinflammatory effects and has been shown to reduce superoxide generation in damaged tissues, and protects against tissue damage following myocardial ischemia, mediated via an interaction with ATP-sensitive potassium channels.
Excerpted from Wikipedia’s “CP-532,903” article, available under the CC BY-SA 4.0 licence.