cycrimine

Also known as alpha-Cyclopentyl-alpha-phenyl-1-piperidinepropanol, Cicrimina, (+-)-Cycrimine, Cycriminum, Pagitane

Cycrimine (trade name Pagitane) is an anticholinergic drug used in the treatment of Parkinson's disease. It is an antagonist of muscarinic acetylcholine receptor M1.

In the Vinony graph

Vinony's link graph records 217 inbound references to cycrimine, and connects out to medication, International Standard Book Number and nervous system.

It sits within the topics 1-Piperidinyl compounds, Antiparkinsonian agents and Cyclopentyl compounds.

Vinony links it to 6 Wikipedia language editions.

Chemical data

Formula: C19H29NO
Molecular weight: 287.4 g/mol
IUPAC name: 1-cyclopentyl-1-phenyl-3-piperidin-1-ylpropan-1-ol
SMILES: C1CCN(CC1)CCC(C2CCCC2)(C3=CC=CC=C3)O
InChIKey: SWRUZBWLEWHWRI-UHFFFAOYSA-N
XLogP: 3.9
Polar surface area: 23.5 Å²
H-bond donors: 1
H-bond acceptors: 2
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1982
Admin. routes: oral

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 287.225
Has use: medication

Show 4 more facts

chemical formula: C₁₉H₂₉NO
Commons category: Cycrimine
canonical SMILES: C1CCN(CC1)CCC(C2CCCC2)(C3=CC=CC=C3)O
World Health Organisation international non-proprietary name: cycrimine

Sources (2)

via Wikidata · CC0

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Encyclopedic overview

4 sections

Contents

Synthesis
See also
References
External links

Cycrimine (trade name Pagitane) is an anticholinergic drug used in the treatment of Parkinson's disease. It is an antagonist of muscarinic acetylcholine receptor M1.

==Synthesis== class=skin-invert-image|thumb|center|500px|Cycrimine synthesis:

Excerpted from Wikipedia’s “cycrimine” article, available under the CC BY-SA 4.0 licence.