DCPS

Also known as DCS1, HINT-5, HINT5, HSL1, ARS, HSPC015, decapping enzyme, scavenger

protein-coding gene in the species Homo sapiens

Gene data

DCPS

Name: decapping enzyme, scavenger
Type: protein-coding
Aliases: ARS, DCS1, HINT-5, HINT5, HSL1, HSPC015

This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5' mRNA cap structure, which appear in the 3' -> 5' mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover. [provided by RefSeq, Apr 2017].

via MyGene.info