DCPS

Name

decapping enzyme, scavenger

Type

protein-coding

Aliases

ARS, DCS1, HINT-5, HINT5, HSL1, HSPC015

This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5' mRNA cap structure, which appear in the 3' -> 5' mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover. [provided by RefSeq, Apr 2017].

via MyGene.info

Gene · Ensembl

decapping enzyme, scavenger

Symbol

DCPS

Biotype

Protein coding

Organism

Homo sapiens

Location

11:126,303,971-126,350,005

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein DCPS PDB 1st0.png

via Wikidata · CC0