Structure via PubChem · Public domain (PubChem)
delamanid
Sign in to saveAlso known as OPC-67683
Delamanid is sold under the brand name Deltyba, is a medication used to treat tuberculosis. Specifically it is used, along with other antituberculosis medications, for active multidrug-resistant tuberculosis. It is taken by mouth.
Chemical data
- Formula
- C25H25F3N4O6
- Molecular weight
- 534.5 g/mol
- IUPAC name
- (2R)-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenoxy]methyl]-3H-imidazo[2,1-b][1,3]oxazole
- SMILES
- C[C@@]1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F
- InChIKey
- XDAOLTSRNUSPPH-XMMPIXPASA-N
- XLogP
- 5.6
- Polar surface area
- 104 Ų
- H-bond donors
- 0
- H-bond acceptors
- 11
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2014
- Indications
- pulmonary tuberculosis, multidrug-resistant tuberculosis, drug-resistant tuberculosis, tuberculosis
via ChEMBL · EBI
Research
716 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 534.173
- Has use
- medication
Show 4 more facts
- chemical formula
- C₂₅H₂₅F₃N₄O₆
- canonical SMILES
- CC1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F
- isomeric SMILES
- C[C@@]1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F
- subject has role
- essential medicine
via Wikidata · CC0
~5 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Adverse effects
- Interactions
- Mechanism of action
- History
- Society and culture
- References
{{Drugbox | image = Delamanid.svg | image_class = skin-invert-image | width = 325 | alt = | caption =
| pronounce = | tradename = Deltyba | Drugs.com = | MedlinePlus = | pregnancy_AU = | pregnancy_category = | routes_of_administration = By mouth | ATCvet = | ATC_prefix = J04 | ATC_suffix = AK06
Excerpted from Wikipedia’s “delamanid” article, available under the CC BY-SA 4.0 licence.