Structure via PubChem · Public domain (PubChem)
protionamide
Sign in to saveAlso known as prothionamide
Protionamide (or prothionamide) is a medication used in the treatment of tuberculosis and leprosy.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 447906208
- Drug.IUPAC_name
- 2-propylpyridine-4-carbothioamide
- Drug.image
- Protionamide.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Prothionamide 3D ball.png
- Drug.image_class2
- bg-transparent
- Drug.ATC_prefix
- J04
- Drug.ATC_suffix
- AD01
- Drug.CAS_number
- 14222-60-7
- Drug.PubChem
- 666418
- Drug.DrugBank
- DB12667
- Drug.UNII
- 76YOO33643
- Drug.ChemSpiderID
- 579891
- Drug.C
- 9
- Drug.H
- 12
- Drug.N
- 2
via Wikipedia infobox
Chemical data
- Formula
- C9H12N2S
- Molecular weight
- 180.27 g/mol
- IUPAC name
- 2-propylpyridine-4-carbothioamide
- SMILES
- CCCC1=NC=CC(=C1)C(=S)N
- InChIKey
- VRDIULHPQTYCLN-UHFFFAOYSA-N
- XLogP
- 1.5
- Polar surface area
- 71 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
416 papers- Prothionamide.2006
- Prothionamide.Tuberculosis (Edinburgh, Scotland) · 2008
- Drug-induced hypothyroidism in tuberculosis.Expert review of endocrinology & metabolism · 2024
- [Clinical analysis of protionamide and para-aminosalicylic acid induced hepatotoxicity in 129 cases].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases · 2013
- Validation of a universal and highly sensitive two-dimensional liquid chromatography-tandem mass spectrometry methodology for the quantification of pyrazinamide, ethambutol, protionamide, and clofazimine in different biological matrices.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2020
via PubMed
Wikidata facts
- Mass
- 180.072
Show 3 more facts
- chemical formula
- C₉H₁₂N₂S
- canonical SMILES
- CCCC1=NC=CC(=C1)C(=S)N
- Commons category
- Protionamide
Sources (2)
via Wikidata · CC0
~1 min read
Article
1 sectionsContents
- References
Protionamide (or prothionamide) is a medication used in the treatment of tuberculosis and leprosy.
Protionamide is a therapeutic alternative on the World Health Organization's List of Essential Medicines.
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via Wikidata sitelinks · CC0
Connections
4-aminosalicylic acid
Entity
medication
Entity
World Health Organization
Entity
tuberculosis
Entity
leprosy
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digital object identifier
Entity
infection
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chemical formula
Entity
molar mass
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L-alanine
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Q180686
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CAS Registry Number
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streptomycin
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Q229883
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PubChem
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Anatomical Therapeutic Chemical Classification System
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peptidoglycan
Entity
clinical trial
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RNA polymerase
Entity
World Health Organization Model List of Essential Medicines
Entity