Structure via PubChem · Public domain (PubChem)
dexketoprofen
Sign in to saveAlso known as (+)-ketoprofen, (+)-3-benzoylhydratropic acid, (+)-(S)-m-benzoylhydratropic acid, (S)-3-benzoyl-alpha-methylbenzeneacetic acid, (S)-ketoprofen
Dexketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It is manufactured by Menarini, under the tradename Keral. It is available in the UK, as dexketoprofen trometamol, as a prescription-only drug and in Latin America as Enantyum, produced by Menarini. Also, in Italy and Spain it is available as an over-the-counter drug (OTC) under the trade name Enandol or Enantyum. In Hungary it is available from a pharmacy as Ketodex. In Turkey, it is an over the counter medicine under the name Arveles. In Latvia, Lithuania and Estonia it is available as an OTC under the tradename Dolmen. In Mexic
Chemical data
- Formula
- C16H14O3
- Molecular weight
- 254.28 g/mol
- IUPAC name
- (2S)-2-(3-benzoylphenyl)propanoic acid
- SMILES
- C[C@@H](C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O
- InChIKey
- DKYWVDODHFEZIM-NSHDSACASA-N
- XLogP
- 3.1
- Polar surface area
- 54.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 254.094294
Show 5 more facts
- chemical formula
- C₁₆H₁₄O₃
- canonical SMILES
- CC(C1=CC=CC(=C1)C(=O)C2=CC=CC=C2)C(=O)O
- isomeric SMILES
- C[C@@H](C1=CC=CC(=C1)C(=O)C2=CC=CC=C2)C(=O)O
- defined daily dose
- 75
- World Health Organisation international non-proprietary name
- dexketoprofen
Sources (3)
via Wikidata · CC0
~2 min read
Article
6 sectionsContents
- Chemistry
- Medical uses
- Side effects
- Pharmacology
- See also
- References
Dexketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It is manufactured by Menarini, under the tradename Keral. It is available in the UK, as dexketoprofen trometamol, as a prescription-only drug and in Latin America as Enantyum, produced by Menarini. Also, in Italy and Spain it is available as an over-the-counter drug (OTC) under the trade name Enandol or Enantyum. In Hungary it is available from a pharmacy as Ketodex. In Turkey, it is an over the counter medicine under the name Arveles. In Latvia, Lithuania and Estonia it is available as an OTC under the tradename Dolmen. In Mexico it is available in tablet form as Stadium made by Menarini. It is the dextrorotatory stereoisomer of ketoprofen.
== Chemistry == Dexketoprofen is the (S)-enantiomer of ketoprofen. Technically it is a chiral switch of (±)-ketoprofen. The switch was done for a faster onset of action and a better therapeutic value. Dexketoprofen consists of a propionic acid moiety connected to a benzophenone molecule by its second carbon.