Structure via PubChem · Public domain (PubChem)
dekstrotyroksyna
Sign in to saveAlso known as Choloxin®, D-T4, D-thyroxine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine, DT4, Dextrothyroxine, O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine
związek chemiczny
In the Vinony graph
Vinony's link graph records 145 inbound references to dekstrotyroksyna, and connects out to propranolol, hypolipidemic and liver.
It sits within the topics Diphenyl ethers, Drugs with no legal status and ECHA InfoCard ID from Wikidata.
Vinony links it to 11 Wikipedia language editions.
Chemical data
- Formula
- C15H11I4NO4
- Molecular weight
- 776.87 g/mol
- IUPAC name
- (2R)-2-azaniumyl-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1967
- Admin. routes
- oral
- Indications
- cardiovascular disease, Down syndrome
via ChEMBL · EBI
Research
309 papers- THE EFFECTS OF DEXTROTHYROXINE IN DIABETES.California medicine · 1964
- Dextrothyroxine.New York state journal of medicine · 1972
- Comparative effectiveness of dextrothyroxine and levothyroxine in correcting hypothyroidism and lowering blood lipid levels in hypothyroid patients.The Journal of clinical endocrinology and metabolism · 1979
- Dextrothyroxine for lowering cholesterol.The Medical letter on drugs and therapeutics · 1976
- Adverse effects of hypolipidaemic drugs.Medical toxicology · 1987
via PubMed
Wikidata facts
- Subclass of
- thyroxine
- Mass
- 776.6867
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₅H₁₁I₄NO₄
- medical condition treated
- coronary artery disease
- canonical SMILES
- C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)O)N
- isomeric SMILES
- C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@H](C(=O)O)N
- defined daily dose
- 4
Sources (3)
via Wikidata · CC0
Available in 11 languages
via Wikidata sitelinks · CC0
Connections
propranolol
Entity
hypolipidemic
Entity
liver
Entity
medication
Entity
iodine
Entity
selenium
Entity
enzyme
Entity
circulatory system
Entity
blood vessel
Entity
digital object identifier
Entity
chemical formula
Entity
molar mass
Entity
PubMed
Entity
dietary fiber
Entity
triglyceride
Entity
L-tyrosine
Entity
CAS Registry Number
Entity
blood serum
Entity
isomer
Entity
gastrointestinal tract
Entity