Structure via PubChem · Public domain (PubChem)
diflucortolone
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Diflucortolone (INN), or difluocortolone, is a corticosteroid.
Chemical data
- Formula
- C22H28F2O4
- Molecular weight
- 394.5 g/mol
- IUPAC name
- (6S,8S,9R,10S,11S,13S,14S,16R,17S)-6,9-difluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one
- SMILES
- C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@H]1C(=O)CO)C)O)F)C)F
- InChIKey
- OGPWIDANBSLJPC-RFPWEZLHSA-N
- XLogP
- 2.3
- Polar surface area
- 74.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
148 papers- Diflucortolone valerate. Asian experience.Drugs · 1988
- Treatment of angular cheilitis: A narrative review and authors' clinical experience.Oral diseases · 2020
- Cutaneous polyarteritis nodosa successfully treated with topical diflucortolone valerate: a case report & review of the literature.Pediatric rheumatology online journal · 2014
- The association of isoconazole-diflucortolone in the treatment of pediatric tinea corporis.The Journal of dermatological treatment · 2018
- Treatment of postscabies prurigo with diflucortolone and chlorquinaldol in a group of African refugees.Tropical doctor · 2019
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 394.195566
- Has use
- medication
Show 5 more facts
- chemical formula
- C₂₂H₂₈F₂O₄
- canonical SMILES
- CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1C(=O)CO)C)O)F)C)F
- isomeric SMILES
- C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@H]1C(=O)CO)C)O)F)C)F
- subject has role
- anti-inflammatory agent
- medical condition treated
- skin disease
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Diflucortolone (INN), or difluocortolone, is a corticosteroid.
== See also == Diflucortolone valerate
Excerpted from Wikipedia’s “diflucortolone” article, available under the CC BY-SA 4.0 licence.