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Structure via PubChem · Public domain (PubChem)
elsamitrucin
Sign in to saveAlso known as elsamicin A
Elsamitrucin (elsamicin A) is a drug used in chemotherapy. Elsamitrucin is chemically related to chartreusin.
In the Vinony graph
Vinony's link graph records 274 inbound references to elsamitrucin, and connects out to tiazofurin, medication and digital object identifier.
It is catalogued under topics including Aminoglycoside antibiotics, Antineoplastic drugs and Chemical pages without DrugBank identifier.
Vinony links it to 6 Wikipedia language editions.
Chemical data
- Formula
- C33H35NO13
- Molecular weight
- 653.6 g/mol
- IUPAC name
- 3-[(2S,3R,4S,5S,6R)-3-[(2R,3R,4R,5S,6R)-3-amino-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-8-hydroxy-15-methyl-11,18-dioxapentacyclo[10.6.2.02,7.09,19.016,20]icosa-1(19),2(7),3,5,8,12(20),13,15-octaene-10,17-dione
- SMILES
- C[C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O[C@H]2[C@@H](O[C@@H]([C@@H]([C@]2(C)O)O)C)OC3=CC=CC4=C3C5=C6C7=C(C=CC(=C7C(=O)O5)C)OC(=O)C6=C4O)N)OC)O
- InChIKey
- MGQRRMONVLMKJL-KWJIQSIXSA-N
- XLogP
- 2
- Polar surface area
- 206 Ų
- H-bond donors
- 5
- H-bond acceptors
- 14
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Oligosaccharide
via ChEMBL · EBI
Research
33 papers- An open-label, dose-escalating phase I study of elsamitrucin (SPI 28090) in treatment of malignant solid tumors in dogs.Journal of veterinary internal medicine · 2011
- Phase II study of elsamitrucin in non-small cell lung cancer.Investigational new drugs · 1994
- Phase II study of elsamitrucin (BMY-28090) for the treatment of patients with refractory/relapsed non-Hodgkin's lymphoma.Investigational new drugs · 1996
- Determination of Elsamitrucin (BMY-28090) in plasma and urine by high-performance liquid chromatography with fluorescence detection.Journal of chromatography · 1993
- Phase I trial and clinical pharmacology of elsamitrucin.Cancer research · 1992
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 653.211
- Has use
- medication
Show 3 more facts
- chemical formula
- C₃₃H₃₅NO₁₃
- canonical SMILES
- CC1C(C(C(C(O1)OC2C(OC(C(C2(C)O)O)C)OC3=CC=CC4=C3C5=C6C7=C(C=CC(=C7C(=O)O5)C)OC(=O)C6=C4O)N)OC)O
- isomeric SMILES
- C[C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O[C@H]2[C@@H](O[C@@H]([C@@H]([C@]2(C)O)O)C)OC3=CC=CC4=C3C5=C6C7=C(C=CC(=C7C(=O)O5)C)OC(=O)C6=C4O)N)OC)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Elsamitrucin (elsamicin A) is a drug used in chemotherapy. Elsamitrucin is chemically related to chartreusin.
== References ==
Excerpted from Wikipedia’s “elsamitrucin” article, available under the CC BY-SA 4.0 licence.