Structure via PubChem · Public domain (PubChem)
eprazinone
Sign in to saveAlso known as Éprazinone, 3-(4-(beta-Ethoxyphenethyl)-1-piperazinyl)-2-methylpropiophenone, 1-(2-Phenyl-2-ethoxyethyl)-4-(2-benzyloxypropyl)piperazine
Eprazinone (trade names Eftapan, Isilung, Mucitux) is a mucolytic and bronchospasm relieving drug. It has been marketed in many European countries, but not in the US or United Kingdom.
Chemical data
- Formula
- C24H32N2O2
- Molecular weight
- 380.5 g/mol
- IUPAC name
- 3-[4-(2-ethoxy-2-phenylethyl)piperazin-1-yl]-2-methyl-1-phenylpropan-1-one
- SMILES
- CCOC(CN1CCN(CC1)CC(C)C(=O)C2=CC=CC=C2)C3=CC=CC=C3
- InChIKey
- BSHWLCACYCVCJE-UHFFFAOYSA-N
- XLogP
- 3.7
- Polar surface area
- 32.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
22 papers- Eprazinone alters lung lavage lipid levels and transtracheal ion transport.Experimental lung research · 1992
- Pharmacophore modeling, virtual screening, and in vitro testing reveal haloperidol, eprazinone, and fenbutrazate as neurokinin receptors ligands.Journal of chemical information and modeling · 2014
- Effects of automated external lubrication on tablet properties and the stability of eprazinone hydrochloride.International journal of pharmaceutics · 2009
- [Therapy of bronchitis in childhood with Eprazinone (author's transl)].Padiatrie und Padologie · 1980
- [Eprazinone exanthema with subcorneal pustulosis].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 1984
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 380.246
- Has use
- medication
Show 5 more facts
- defined daily dose
- 0.2
- canonical SMILES
- CCOC(CN1CCN(CC1)CC(C)C(=O)C2=CC=CC=C2)C3=CC=CC=C3
- chemical formula
- C₂₄H₃₂N₂O₂
- World Health Organisation international non-proprietary name
- eprazinone
- subject has role
- mucokinetic
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Indications
- Side effects
- References
Eprazinone (trade names Eftapan, Isilung, Mucitux) is a mucolytic and bronchospasm relieving drug. It has been marketed in many European countries, but not in the US or United Kingdom.
==Indications== Indications include acute and chronic bronchitis, cough, rhinitis, and asthma.
Excerpted from Wikipedia’s “eprazinone” article, available under the CC BY-SA 4.0 licence.