ERRFI1

Also known as GENE-33, MIG-6, MIG6, RALT, ERBB receptor feedback inhibitor 1

ERBB receptor feedback inhibitor 1 is a protein that in humans is encoded by the ERRFI1 gene.

Gene data

ERRFI1

Name: ERBB receptor feedback inhibitor 1
Type: protein-coding
Position: 8,004,404–8,026,312 (−)
Aliases: GENE-33, MIG-6, MIG6, RALT
Ensembl: ENSG00000116285
RefSeq RNA: NM_018948.4, XM_005263477.4, XM_047422698.1, XM_047422701.1, XM_054337101.1
RefSeq protein: NP_061821.1, XP_005263534.1, XP_047278654.1, XP_047278657.1, XP_054193076.1

ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM, Mar 2008].

Pathways

Glioblastoma signaling pathways EGF-EGFR signaling pathway

via MyGene.info

Gene · Ensembl

ERBB receptor feedback inhibitor 1

Symbol: ERRFI1
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:8,003,196-8,026,318
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein ERRFI1 PDB 2RF9.png

Show 5 more facts

HomoloGene ID: 10344
exact match: identifiers.org/ncbigene/54206
genomic end: 8026309
genomic start: 8064464
cytogenetic location: 1p36.23

Sources (4)

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ERBB receptor feedback inhibitor 1 is a protein that in humans is encoded by the ERRFI1 gene.

MIG6 is a Cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000; Fiorentino et al., 2000).