Structure via PubChem · Public domain (PubChem)
famotidine
Sign in to saveAlso known as Gaster®, MK-208, Pepcid®, N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide, 3-(((2-((Diaminomethylene)amino)-4-thiazolyl)methyl)thio)-N(sup 2)-sulfamoylpropionamidine, 3-(((2-((Aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-N-(aminosulfonyl)propanimidamide, (1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide, Quamtel
Famotidine, sold under the brand name Pepcid among others, is a histamine H2 receptor antagonist medication that decreases stomach acid production. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. It is taken by mouth or by injection into a vein. It begins working within an hour.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 458958452
- Drug.image
- Famotidine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 275
- Drug.image2
- File:Famotidine-from-xtal-Mercury-3D-bs.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Pepcid, Zantac 360, others
- Drug.MedlinePlus
- a687011
- Drug.DailyMedID
- Famotidine
- Drug.pregnancy_AU
- B1
- Drug.routes_of_administration
- Oral, intravenous
- Drug.class
- Histamine H2 receptor antagonist
- Drug.ATC_prefix
- A02
- Drug.ATC_suffix
- BA03
- Drug.legal_AU
- S3
- Drug.legal_AU_comment
- / S4
- Drug.legal_UK
- POM
via Wikipedia infobox
Chemical data
- Formula
- C8H15N7O2S3
- Molecular weight
- 337.5 g/mol
- IUPAC name
- 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N'-sulfamoylpropanimidamide
- SMILES
- C1=C(N=C(S1)N=C(N)N)CSCC/C(=N\S(=O)(=O)N)/N
- InChIKey
- XUFQPHANEAPEMJ-UHFFFAOYSA-N
- XLogP
- -0.6
- Polar surface area
- 238 Ų
- H-bond donors
- 4
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Research
2,677 papers- Famotidine Repurposing for Novel Corona Virus Disease of 2019: A Systematic Review.Drug research · 2021
- Famotidine increases cellular phospho-tyrosine levels.Biochemical and biophysical research communications · 2024
- Famotidine in gastroesophageal reflux disease (GERD).Hepato-gastroenterology · 1992
- Clinical pharmacokinetics of famotidine.Clinical pharmacokinetics · 1991
- Famotidine in the management of schizophrenia.The Annals of pharmacotherapy · 1999
via PubMed
Wikidata facts
- Subclass of
- H2 antagonists
- Mass
- 337.044936
- Has use
- medication
Show 8 more facts
- chemical formula
- C₈H₁₅N₇O₂S₃
- Commons category
- Famotidine
- canonical SMILES
- C1=C(N=C(S1)N=C(N)N)CSCCC(=NS(=O)(=O)N)N
- isomeric SMILES
- C1=C(N=C(S1)N=C(N)N)CSCC/C(=N/S(=O)(=O)N)/N
- World Health Organisation international non-proprietary name
- famotidine
- has characteristic
- bitterness
- defined daily dose
- 40
- significant drug interaction
- ketoconazole
via Wikidata · CC0
~9 min read
Encyclopedic overview
13 sectionsContents
- Medical uses
- Pharmacokinetics
- Side effects
- Mechanism of action
- Interactions
- History
- Society and culture
- Research
- COVID-19
- Other
- Veterinary uses
- References
- External links
{{Infobox drug | Watchedfields = changed | verifiedrevid = 458958452 | image = Famotidine.svg | image_class = skin-invert-image | width = 275 | alt = | image2 = File:Famotidine-from-xtal-Mercury-3D-bs.png | image_class2 = bg-transparent | alt2 = | caption =
| pronounce = | tradename = Pepcid, Zantac 360, others | Drugs.com = | MedlinePlus = a687011 | DailyMedID = Famotidine | pregnancy_AU = B1 | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = Oral, intravenous | class = Histamine H2 receptor antagonist | ATC_prefix = A02 | ATC_suffix = BA03 | ATC_supplemental =
Excerpted from Wikipedia’s “famotidine” article, available under the CC BY-SA 4.0 licence.