FANCF
Sign in to saveAlso known as FAF, Fanconi anemia complementation group F, FA complementation group F
Fanconi anemia group F protein is a protein that in humans is encoded by the FANCF gene.
Gene data
FANCF- Name
- FA complementation group F
- Type
- protein-coding
- Aliases
- FAF
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group F. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
FA complementation group F
- Symbol
- FANCF
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:22,622,533-22,625,823
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein FANCF PDB 2iqc.png
Show 5 more facts
- HomoloGene ID
- 75185
- exact match
- identifiers.org/ncbigene/2188
- genomic end
- 22625823
- genomic start
- 22622533
- cytogenetic location
- 11p14.3
Sources (7)
via Wikidata · CC0
~4 min read
Article
7 sectionsContents
- Interactions
- Function
- Cancer
- Infertility
- References
- Further reading
- External links
Fanconi anemia group F protein is a protein that in humans is encoded by the FANCF gene.
== Interactions ==