FHL5

Also known as ACT, dJ393D12.2, 1700027G07Rik, FHL-5, four and a half LIM domains 5

Four and a half LIM domains protein 5 is a protein that in humans is encoded by the FHL5 gene.

In the Vinony graph

Within Vinony's link graph, FHL5 is referenced by 5 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 6.

Its subject is documented across 6 Wikipedia language editions.

Gene data

FHL5

Name: four and a half LIM domains 5
Type: protein-coding
Position: 96,562,548–96,621,381 (+)
Aliases: 1700027G07Rik, ACT, FHL-5, dJ393D12.2
Ensembl: ENSG00000112214
RefSeq RNA: NM_001170807.3, NM_001322466.2, NM_001322467.1, NM_020482.6, XM_047419567.1
RefSeq protein: NP_001164278.1, NP_001309395.1, NP_001309396.1, NP_065228.4, XP_047275523.1

The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Polymorphisms in this gene may be associated with susceptibility for migraine headaches. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Apr 2016].