Structure via PubChem · Public domain (PubChem)
fluprednisolone
Sign in to saveAlso known as 6alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione, 6alpha-Fluoroprednisolone, Fluprednisolonum
Fluprednisolone is a pregnane. It is a corticosteroid.
In the Vinony graph
Within Vinony's link graph, fluprednisolone is referenced by 272 other articles, and connects out to mometasone furoate, fludrocortisone and ulipristal acetate.
It is catalogued under topics including Chembox image size set, Corticosteroids and ECHA InfoCard ID from Wikidata.
Its subject is documented across 8 Wikipedia language editions.
Chemical data
- Formula
- C21H27FO5
- Molecular weight
- 378.4 g/mol
- IUPAC name
- (6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
- SMILES
- C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)C[C@@H](C4=CC(=O)C=C[C@]34C)F)O
- InChIKey
- MYYIMZRZXIQBGI-HVIRSNARSA-N
- XLogP
- 1.4
- Polar surface area
- 94.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- oral
via ChEMBL · EBI
Research
330 papers- [Fluprednisolone in the practice of pediatrics].Prensa medica argentina · 1967
- [Fluprednisolone, a corticosteroid of slight diabetogenic effect].Arzneimittel-Forschung · 1970
- Difluprednate for inflammatory eye disorders.Drugs of today (Barcelona, Spain : 1998) · 2011
- [Pseudohyperaldosteronism].Revista clinica espanola · 1984
- Fluprednisolone, a new corticosteroid, in treating allergies.The Journal of new drugs · 1961
via PubMed
Wikidata facts
- Mass
- 378.184
Show 5 more facts
- chemical formula
- C₂₁H₂₇FO₅
- canonical SMILES
- CC12CC(C3C(C1CCC2(C(=O)CO)O)CC(C4=CC(=O)C=CC34C)F)O
- isomeric SMILES
- C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)C[C@@H](C4=CC(=O)C=C[C@]34C)F)O
- subject has role
- glucocorticoid
- Commons category
- Fluprednisolone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Fluprednisolone is a pregnane. It is a corticosteroid.
==References==
Excerpted from Wikipedia’s “fluprednisolone” article, available under the CC BY-SA 4.0 licence.