(±)-flurbiprofen
Also known as Ansaid®, Froben®, 3-fluoro-4-phenylhydratropic acid, 2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid, (+-)-2-fluoro-alpha-methyl-4-biphenylacetic acid, Flurbiprofen, Ansaid, 2-(2-fluorobiphenyl-4-yl)propanoic acid
Flurbiprofen is a member of the phenylalkanoic acid derivative family of nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily indicated as a pre-operative anti-miotic (in an ophthalmic solution) as well as orally for arthritis or dental pain. Side effects are analogous to those of ibuprofen.
Chemical data
- Formula
- C15H13FO2
- Molecular weight
- 244.26 g/mol
- IUPAC name
- 2-(3-fluoro-4-phenylphenyl)propanoic acid
- SMILES
- CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O
- InChIKey
- SYTBZMRGLBWNTM-UHFFFAOYSA-N
- XLogP
- 4.2
- Polar surface area
- 37.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
3,206 papers~2 min read
Article
5 sectionsContents
- Adverse effects
- Society and culture
- Brand names
- References
- Further reading
Flurbiprofen is a member of the phenylalkanoic acid derivative family of nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily indicated as a pre-operative anti-miotic (in an ophthalmic solution) as well as orally for arthritis or dental pain. Side effects are analogous to those of ibuprofen.
It was derived from propionic acid by the research arm of Boots UK during the 1960s, a period which also included the discovery of ibuprofen, indometacin, diclofenac, naproxen, ketoprofen, and sulindac.